Male gonadal axis assessment in bariatric surgery candidates

Results We evaluated 69 subjects, mean age 39±10 yrs. and 87% caucasian. Type 2 Diabetes Mellitus (T2D) was found in 47.8%, hypertension in 72.5%, dyslipidemia in 23.2% and metabolic syndrome according to the IDF in 87%. Mean weight, waist circumference and BMI were respectively: 157.4±31.0 kg, 148.2±14.9 cm and 51.2±8.3 kg/m2. The average fasting glycemia was 111.1±34.7 mg/dL (NR <100), HbA1c 6.5±1.3% (NR <5.7), total testosterone (TT) 232.8±96.9 ng/dL (NR >300), LH 3.1±1.3 mUmL (NR 0.8 to 7.6) and calculated free testosterone (CFT) 5.9±2.7 ng/dL (NR> 6.5). 79.7% of subjects had TT ≤ 300 ng/dL and 56.5% CFT ≤ 6.5 ng/dL. Categorizing patients according to the levels of TT [G1 (≤ 200 ng/dL): 53.8±8.5 kg/m2 x G2 (201-299 ng/dL): 49.3±7.2 kg/m2 x G3 (≥ 300 ng/dL): 48.7±8.7 kg/m2], there was a statistically significant difference only in relation to BMI (p=0.04). There were no statistically significant differences in mean TT and CFT between individuals with and without T2D [TT: 218.8±89.4 x 245.5±102.8 ng/dL (p=0.25); CFT: 5.65±2.7 x 2.6±6.21 ng/dL (p=0.39)].